姜磊（副教授）

  姓    名：

姜磊

  职    称：

副教授

  导师类别：

　硕导

  系    室：

 生物与能源化工系

  研究领域：

　生物材料，生物传感，检验检测

  电子邮箱：

Leijiang@upc.edu.cn

  联系电话：

13280884087

◎教育背景

1996-2000，南开大学生命科学学院生物化学与分子生物学系，理学学士

2000-2004， 英国牛津大学物理及理论化学系，博士

◎工作经历

2004-2009， 英国牛津大学病理学院免疫系，博士后

2009-2012， 新西兰恒天然集团公司乳制品研究所，研究科学家

2012-，      365游戏大厅(华东)化工学院生物与能源化工系，副教授

◎研究方向

[1] 生物传感，生物分析与检测，仿生纳米材料，生物高分子

[2] 生物医学应用，食品安全检测，生物芯片设计

[3] 有机毒害物的痕量检测和快速降解

[4] 表界面摩擦和润滑

◎科研项目

[1] 科技部863计划青年科学家专题项目，一种强穿透性和靶向性的新型生物光敏剂的开发及其对肿瘤治疗的功效评价2015AA020947。

[2] 国家自然科学基金青年基金，多价离子对高分子电解质透明质酸构象的影响及其相互作用的分子机理研究，21204102。

[3] 国家自然科学基金石油化工联合基金，纳米颗粒与表面活性剂形成的超分子稳定结构及稳定驱油泡沫的分子机理研究，U1262102。

[4] 山东省重点研发计划，基于稀土氧化物纳米颗粒的无创血糖检测技术，2018GSF118032。

[5] 山东省自然科学基金，基于稀土氧化物的纳米酶对有机磷农药的降解研究，ZR2017LB028。

[6] 山东省科技发展计划项目，新型复合壳聚糖絮凝剂的开发及其在含聚污水处理中的应用效果评价，2014GHY115020。

[7] 365游戏大厅（华东）青年骨干教师人才建设工程项目。

[8] 365游戏大厅（华东）自主创新科研计划项目。

◎代表性论文及专利

1.论文

[1] Enhanced Artificial Enzyme Activities on the Reconstructed Sawtoothlike Nanofacets of Pure and Pr-Doped Ceria Nanocubes, Lei Jiang,* Miguel Tinoco, Susana Fernández-García, Yujiao Sun, Mariia Traviankina, Pengli Nan, Qi Xue, Huiyan Pan, Almudena Aguinaco, Juan M. González-Leal, Ginesa Blanco, Eduardo Blanco, Ana B. Hungría, Jose J. Calvino, and Xiaowei Chen*, ACS Applied Materials & Interfaces, 2021, 13, 38061−38073

[2] A syringe-aided apta-nanosensing method for colorimetric determination of acetamiprid, Limin Yang, Xuan Wang, Haifeng Sun, Weijing Yao, Zhen Liu*, Lei Jiang*, Analytica Chimica Acta 1150 (2021) 238118.

[3] Fabrication of denatured BSA-hemin-IR780 (dBHI) nanoplatform for synergistic combination of phototherapy and chemodynamic therapy, Nannan Zheng , Yitong Chen , Lei Jiang , Hongchao Ma*, Colloids and Surfaces A, 634 (2022) 127957.

[4] Laccase-like catalytic activity of Cu-tannic acid nanohybrids and their application for epinephrine detection, Hongchao Ma*, Nannan Zheng , Yitong Chen , Lei Jiang*, Colloids and Surfaces A, 613 (2021) 126105.

[5] A colorimetric aptasensing assay with adjustable color mutation points for threshold-readout detection of carcinoembryonic antigen, Limin Yang*, Meng Cui, Yiping Zhang, Lei Jiang, Hanyun Liu, Zhen Liu *, Sensors & Actuators: B. Chemical 350 (2022) 130857

[6] 聚去甲肾上腺素构建的多功能仿生表界面, 韩亚宁，刘涵云，冯卫华，马洪超，杨丽敏，姜磊*，中国表面工程，2021， 34（3），40-58.

[7] Photocatalytically renewable peptide-based electrochemical impedance method for sensing lipopolysaccharide, Limin Yang*, Yukun Gao, Kai Fang, Hui Sun, Jingtao Sun, Hanyun Liu, Weihua Feng, Lei Jiang*, Microchimica Acta, 2020, 187, 349.

[8] From DNA to Nerve Agents – The Biomimetic Catalysts for the Hydrolysis of Phosphate Esters

Lei Jiang*, Yujiao Sun, Yuxue Chen, and Pengli Nan, ChemistrySelect 2020, 5, 9492 –9516.

[9] An enzyme inhibition-based lab-in-a-syringe device for point-of-need determination of

Pesticides, Limin Yang*, Jinxin Wang, Linjiao Qu, Zhen Liu*, Lei Jiang*, Analyst, 2020, 145, 3958–3966.

[10] Polydopamine-induced fabrication of Ag-TiO2 hollow nanospheres and their application in visible-light photocatalysis, Hongchao Ma*; Wenbo Zheng; Xin Yan; Kai Zhang; Guojun Liu; Lei Jiang*, Colloids and Surfaces A, 2020, 2020(586): 123283.

[11] An aptamer based aggregation assay for the neonicotinoid insecticide acetamiprid using fluorescent upconversion nanoparticles and DNA functionalized gold nanoparticles, Limin Yang; Haifeng Sun; Xuan Wang; Weijing Yao; Wenjuan Zhang; Lei Jiang*, Microchimica Acta, 2019, 2019(186): 308.

[12] Controlled morphology evolution of branched Au nanostructures and their shape-dependent catalytic and photo-thermal properties, Hongchao Ma*; Zhibin Liu; Yanhui Wei; Lei Jiang*, Colloids and Surfaces A, 2019, 2019(512): 123889.

[13] Fabrication of polydopamine-based layer-by-layer nanocomposites for combined pH-sensitive chemotherapy and photothermal therapy, Hongchao Ma; Shuo Li; Hao Zhang; Lei Jiang*, Colloids and Surfaces A, 2019, 2019(561): 332-340.

[14] Selective oxidation of glycerol on morphology controlled ceria nanomaterials, Miguel Tinoco, Susana Fernandez-Garcia, Alberto Villa, Juan M. Gonzalez, Ginesa Blanco, Ana B. Hungria, Lei Jiang, Laura Prati, Jose J. Calvino, Xiaowei Chen*, Catalysis Science & Technology, 2019, 9, 2328.

[15] Determination of Organophosphorus Pesticides in Fortified Tomatoes by Fluorescence Quenching of Cadmium Selenium – Zinc Sulfide Quantum Dots, Limin Yang; Xiaohui Zhang; Lei Jiang*, analytical letters, 2018, 52(5): 724-744.

[16] Double-decrease of the fluorescence of CdSe/ZnS quantum dots for the detection of zinc(II) dimethyldithiocarbamate (ziram) based on its interaction with gold nanoparticles, Limin yang; Xiaohui Zhang; Jinxin Wang; Haifeng Sun; Lei Jiang*, Microchimica Acta, 2018, 185(10): 472.

[17] Molecular weight impact on the mechanical forces between hyaluronan and its receptor, Lei Jiang*; Guihua Liu; Hanyun Liu; Zhibin Liu; Hongchao Ma, Carbohydrate Polymers, 2018, 197: 326-336.

[18] A non-enzymatic nanoceria electrode for non-invasive glucose monitoring, Lei Jiang*; Qi Xue; Chuanjie Jiao; Hanyun Liu; Yan Zhou; Hongchao Ma; Qingli Yang, Analytical Methods, 2018, 10: 2151-2159.

[19] The Impact of Ionic Liquid and Nanoparticles on Stabilizing Foam for Enhanced Oil Recovery, Lei Jiang*; Jingtao Sun; Jiqian Wang; Songyan Li; Wenyang Yu; Zhaomin Li*, ChemistrySelect, 2018, 3: 12461-12468.

[20] Fabrication of Two-dimensional (2D) Ordered Microsphere Aligned by Supramolecular Self-Assembly of Formyl-Azobenzene and Dipeptide, Hongchao Ma; Yanhui Wei; Lei Jiang*; Junbai Li*, Journal of Colloid and Interface Science, 2018, 514: 491-495.

[21] 量子点传感器在有机磷农药残留检测中的应用, 张晓慧; 杨丽敏; 马洪超; 姜磊*, 化学通报, 2017, 80(11): 1014-1020.

[22] 稀土上转换纳米载体的构建及功能化修饰机制的研究进展, 燕照霞; 姜磊*; 刘涵云; 李文静; 刘艺炜; 华放, 中国稀土学报, 2017, 35(3): 301-314.

[23] Improved Oxidase Mimetic Activity by Praseodymium Incorporation into Ceria Nanocubes, Lei Jiang*; susana fernandez-garcia; miguel Tinoco; Zhaoxia Yan; Qi Xue; Ginesa Blanco; Jose J. Calvino; Ana B. Hungria; Xiaowei Chen*, ACS Applied Materials & Interfaces, 2017, 9: 18595-18608.

[24] Hyaluronan–tyrosine–gold nanoparticles as an enzyme-free colorimetric probe for the detection of phosphorothiolate pesticides, Limin yang; Xiaohui Zhang; Huiping Li; Lei Jiang*, Analytical Methods, 2017, 9: 6139.

[25] Fabrication of photonic quasicrystalline structures in the sub-micrometer scale, Shuai Wang; Xiaohong Sun*; Wenyang Li; Wei Liu; Lei Jiang; Juan Han, Superlattices and Microstructures, 2016, 93: 122-127

[26] Swelling inducedregeneration of TiO2-impregnated chitosan adsorbents under visible light, Limin Yang; Lei Jiang*; Di Hu; Qingyun Yan; Zhi Wang; Sisi Li; Cheng Chen; Qi Xue, Carbohydrate Polymers, 2016, 140: 433-441.

[27] Enhanced Hydroxyl Radical Scavenging Activity by Doping Lanthanum in Ceria Nanocubes, Susana Fernandez-Garcia#; Lei Jiang#; Miguel Tinoco; Ana B. Hungria; Juan Han; Ginesa Blanco; Jose J. Calvino; Xiaowei Chen*, Journal of Physical Chemistry C, 2016, 120(3): 1891-1901.

[28] Interfacial study on theinteraction between hydrophobic nanoparticles and ionic surfactants, Lei Jiang*; Songyan Li; Wenyang Yu; Jiqian Wang; Qian Sun; Zhaomin Li*, Colloids and Surfaces A, 488: 20-27.

[29] Properties of multi-phase foam and its flow behavior in porous media, Qian Sun; Zhaomin Li*; Jiqian Wang; Songyan Li; Lei Jiang; Chao Wang, RSC Advances, 2015, 5: 67676-67689.

[30] Conversion of inhibition biosensing to substrate-like biosensing for quinalphos selective detection, Limin Yang; Juan, Han; Wei Liu; Jiqiang Li; Lei Jiang*, Analytical Chemistry, 2015, 87: 5270-5277.

[31] Aqueous foam stabilized by partially hydrophobic nanoparticles in the presence of surfactant, Qian Sun; Zhaomin Li; Jiqian Wang; Songyan Li; Binfei Li; Lei Jiang; Hongyu Wang; Qichao Lü; Chao Zhang; Wei Liu, Colloids and Surfaces A, 2015, 471(1): 54-64.

[32] Fabrication of ten-fold photonic quasicrystalline structures, XiaoHong Sun; YuLong Wu; Wen Liu; Wei Liu; Juan Han; Lei Jiang, AIP Advances, 2015, 2015(5): 0-57108

[33] Interactions of hyaluronangrafted on protein surfaces studied by quartz crystal microbalance and surfaceforce balance, Lei Jiang*; Juan Han; Limin Yang; Hongchao Ma; Bo Huang, Soft Matter, 2015, 11: 7276-7287.

[34] Surface wettability of oxygen plasma treated porous silicon, Lei Jiang*; Songyan Li; JIqian Wang; Limin Yang; Qian Sun; Zhaomin Li*, Journal of Nanomaterials, 2014, 2014: 0-526149.  

[35] Utilization of Surfactant-Stabilized Foam for Enhanced Oil Recovery by Adding Nanoparticles, Qian Sun; Zhaomin Li; Songyan Li; Lei Jiang; Jiqian Wang; Peng Wang, Energy & Fuels, 2014, 28: 2384-2394.

[36] Real-Time Analysis of Porphyrin J Aggregation on a Plant-Esterase-Functionalized Surface Using Quartz Crystal Microbalance with Dissipation Monitoring, Limin Yang; Lei Jiang*; Weijing Yao; Junling Liu; Juan Han, Langmuir, 2014, 30(33): 9962-9971.

[37] Interactions of hyaluronan layers with similarly-charged surfaces: the effect of divalent cations, Lei Jiang*; Simon Titmuss; Jacob Klein*, Langmuir, 2013, 29(39): 12194-12202.

[38] 氧等离子处理对多孔硅表面润湿性的影响, 姜磊; 李兆敏; 杨丽敏; 李松岩; 孙乾; 张东; 王继乾, 中国表面工程, 2013, 26(5): 43-48

[39] Identification of leukocyte surface protein interaction by high throughput screening with multivalent reagent, Lei Jiang; Neil Barclay*, Immunology, 2010, 129(1): 55-61.

[40] Inhibition of macrophage activation by the myxoma virus M141 protein (vCD200), Liang Zhang; Marianne Stanford; Jia Liu; Catherine Barrett; Lei Jiang; Neil Barclay; Grant McFadden*, Journal of Virology, 2009, 83(18): 9602-9607.

[41] New assay to detect low-affinity interactions & characterization of leukocyte receptors for collagen including leukocyte-associated Ig-like receptor-1 (LAIR-1), Lei Jiang; Neil Barclay*, European Journal of Immunology, 2009, 39(4): 1167-1175.

[42] Direct measurement of forces between cell-coating polymers & chiral crystal surfaces: the enantioselectivity of Hyaluronan, Lei Jiang; Jacob Klein*; Simon Titmuss; Andrew Cowley, Soft Matter, 2008, 4(7): 1521-1530.

2.专利

[1] 一种固化有透明质酸的硅板的制备保存和使用方法

[2] 一种有机磷农药检测方法

[3] 一种检测乐果的纳米材料及其制备方法

[4] 具有pH响应性的均相光催化材料和制备方法及其应用

[5] 一种油气田用荧光二氧化硅纳米颗粒复合泡沫体系

[6] 一种透明质酸薄膜及其应用

[7] 一种用于酸性染料处理的壳聚糖‑TiO2吸附剂的再生方法

[8] 硫代磷酸酯类有机磷农药残留检测试剂盒及其应用方法

[9] 环境友好型超稳定多相泡沫体系及其制备方法

[10] 一种无酶葡萄糖电化学传感器及其应用

[11] 电化学生物传感用自清洁电极

[12] 一种具有肿瘤靶向的褶皱核壳结构的纳米载体

[13] 纳米金固定化小球的制备方法及其在福美锌检测中的应用

[14] 中空双壳二氧化钛纳米颗粒及其应用

[15] 一种多巴胺改性的壳聚糖絮凝剂

[16] 一种用于稠油开采的电加热材料及其制备方法

[17] 一种用于污水处理的复合型絮凝剂

◎代表性著作

[1]

[2]

◎获奖情况及荣誉称号

[1] 2015年，青岛市科学技术奖，科技进步一等奖，花生热榨饼粕深加工技术研究与应用。

[2] 2018年，青岛市科学技术奖，技术发明三等奖，新型光敏材料在有机磷农药检测中的应用。

[3] 2019年，山东省科学技术奖，技术发明三等奖，新型光敏材料在有机磷农药检测中的应用。

[4] 2020年，青岛市青年科技奖

[5] 2014，青岛西海岸新区首批领军人才

◎执教课程

本科生：《实验室安全与环保》《生物科学与工程》《生命科学史》

研究生：《高级生物化学》《生物传感技术及应用》《催化与可再生能源进展》

◎招收及指导研究生情况

1.指导研究生情况

指导学术研究生6名，专业硕士研究生6名。毕业研究生10名，其中3名到国外深造，3名进入机关和事业单位，2名进入科研部门工作。

2.招生专业及要求

招收 生物化工 学术硕士研究生 和 生物与医药 专业硕士研究生

◎学术兼职

[1] 中国生物工程学会青年工作委员会委员